Direct and Stereospecific Synthesis of N-H and N-Alkyl Aziridines from Unactivated Olefins Using Hydroxylamine-O-Sulfonic Acids
Author
Ma, Zhiwei; Zhou, Zhe; Kürti, László
Date
2017Abstract
A RhII-catalyzed direct and stereospecific N-H- and N-alkyl aziridination of olefins is reported that uses hydroxylamine-O-sulfonic acids as inexpensive, readily available, and nitro group-free aminating reagents. Unactivated olefins, featuring a wide range of functional groups, are converted into the corresponding N-H or N-alkyl aziridines in good to excellent yields. This operationally simple, scalable transformation proceeds efficiently at ambient temperature and is tolerant towards oxygen and trace moisture.
Citation
Published Version
Keyword
aziridination; dirhodium catalysis; hydroxylamine-O-sulfonic acid; nitrenoids; olefins
Type
Journal article
Publisher
Citable link to this page
https://hdl.handle.net/1911/98799Rights
This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Wiley.Metadata
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