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    Responsive liquid crystal elastomers for enhanced cell sheet alignment

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    Author
    Verduzco, Rafael; Jacot, Jeffrey G.; Adetiba, Oluwatomiyin; Agrawal, Aditya
    Date
    2017-04-18
    Abstract
    Responsive, biocompatible substrates are of interest for directing the maturation and function of cells in vitro during cell culture. This can potentially provide cells and tissues with desirable properties for regenerative therapies. The present disclosure provides a scalable approach to attach, align and dynamically load cells on responsive liquid crystal elastomer (LCE) substrates. Monodomain LCEs exhibit reversible shape changes in response to cyclic stimulus, and when immersed in an aqueous medium on top of, for example, resistive heaters, shape changes are fast, reversible and produce minimal temperature changes in the surroundings.
    Citation
    Verduzco, Rafael, Jacot, Jeffrey G., Adetiba, Oluwatomiyin and Agrawal, Aditya, "Responsive liquid crystal elastomers for enhanced cell sheet alignment." Patent US9625752Bl. issued 2017-04-18. Retrieved from https://hdl.handle.net/1911/94820.
    Type
    Utility patent
    Citable link to this page
    https://hdl.handle.net/1911/94820
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    Managed by the Digital Scholarship Services at Fondren Library, Rice University
    Physical Address: 6100 Main Street, Houston, Texas 77005
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