Non-Deprotonative Primary and Secondary Amination of (Hetero)Arylmetals
Author
Zhou, Zhe; Ma, Zhiwei; Behnke, Nicole Erin; Gao, Hongyin; Kürti, László
Date
2017Abstract
Herein we disclose a novel method for the facile transfer of primary (−NH2) and secondary amino groups (−NHR) to heteroaryl- as well as arylcuprates at low temperature without the need for precious metal catalysts, ligands, excess reagents, protecting and/or directing groups. This one-pot transformation allows unprecedented functional group tolerance and it is well-suited for the amination of electron-rich, electron-deficient as well as structurally complex (hetero)arylmetals. In some of the cases, only catalytic amounts of a copper(I) salt is required.
Citation
Published Version
Type
Journal article
Publisher
Citable link to this page
https://hdl.handle.net/1911/93785Rights
This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by the American Chemical Society.Metadata
Show full item recordCollections
- Chemistry Publications [636]
- Faculty Publications [4988]