Non-Deprotonative Primary and Secondary Amination of (Hetero)Arylmetals
Author
Zhou, Zhe
Ma, Zhiwei
Behnke, Nicole Erin
Gao, Hongyin
Kürti, László
Date
2017Citation
Published Version
Abstract
Herein we disclose a novel method for the facile transfer of primary (−NH2) and secondary amino groups (−NHR) to heteroaryl- as well as arylcuprates at low temperature without the need for precious metal catalysts, ligands, excess reagents, protecting and/or directing groups. This one-pot transformation allows unprecedented functional group tolerance and it is well-suited for the amination of electron-rich, electron-deficient as well as structurally complex (hetero)arylmetals. In some of the cases, only catalytic amounts of a copper(I) salt is required.
Type
Journal article
Citable link to this page
http://hdl.handle.net/1911/93785Metadata
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