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dc.contributor.authorLaVoy, Emily C.P.
Fagundes, Christopher P.
Dantzer, Robert
dc.date.accessioned 2016-10-21T18:32:23Z
dc.date.available 2016-10-21T18:32:23Z
dc.date.issued 2016
dc.identifier.citation LaVoy, Emily C.P., Fagundes, Christopher P. and Dantzer, Robert. "Exercise, inflammation, and fatigue in cancer survivors." Exercise Immunology Review, 22, (2016) International Society of?Exercise?and?Immunology: 82-93. https://hdl.handle.net/1911/91987.
dc.identifier.urihttps://hdl.handle.net/1911/91987
dc.description.abstract Cancer-related fatigue significantly disrupts normal functioning and quality of life for a substantial portion of cancer survivors, and may persist for years following cancer treatment. While the causes of persistent fatigue among cancer survivors are not yet fully understood, accumulating evidence suggests that several pathways, including chronic inflammation, autonomic imbalance, HPA-axis dysfunction, and/or mitochondrial damage, could contribute towards the disruption of normal neuronal function and result in the symptom of cancer-related fatigue. Exercise training interventions have been shown to be some of the more successful treatment options to address cancer-related fatigue. In this review, we discuss the literature regarding the causes of persistent fatigue in cancer survivors and the mechanisms by which exercise may relieve this symptom. There is still much work to be done until the prescription of exercise becomes standard practice for cancer survivors. With improvements in the quality of studies, evidenced-based exercise interventions will allow exercise scientists and oncologists to work together to treat cancer-related fatigue.
dc.language.iso eng
dc.publisher International Society of?Exercise?and?Immunology
dc.rights This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by International Society ofᅠExerciseᅠandᅠImmunology.
dc.title Exercise, inflammation, and fatigue in cancer survivors
dc.type Journal article
dc.citation.journalTitle Exercise Immunology Review
dc.citation.volumeNumber 22
dc.type.dcmi Text
dc.identifier.pmcid PMC4755327
dc.type.publication post-print
dc.citation.firstpage 82
dc.citation.lastpage 93


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