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Heat transfer to blood
Hetherwick, Robert Murray
Akers, W. W.
Master of Science
In the development of an artificial implantable heart it is necessary to make use of both medical and engineering information. Because the field is fairly new, much of the desired information has not yet been gathered and the purpose of this investigation was to collect some of this information. Studies were made of the heat transfer properties of a blood-Silastic interface and hemolysis tests were made to determine the effects of pumping, turbulence, and temperature on the red blood cells. It was found that a film of biological material built up at the interface and that this film greatly hindered the flow of heat. Studies were made of the growth of this film under various conditions. The hemolysis rate was found to be essentially independent of the amount of turbulence. The studies were made for Reynolds numbers up to approximately 6000. Using a centrifugal pump, it was found that faster impeller rotation speeds resulted in higher hemolysis rates. Higher temperatures generally produced higher hemolysis rates.