Enhanced MRI relaxivity of aquated Gd3+ﾠions by carboxyphenylated water-dispersed graphene nanoribbons
Dimiev, Ayrat M.
Bryant, Robert G.
Tour, James M.
Wilson, Lon J.
The present study demonstrates that highly water-dispersed graphene nanoribbons dispersed by carboxyphenylated substituents and conjugated to aquated Gd3+ﾠions can serve as a high-performance contrast agent (CA) for applications inﾠT1- andﾠT2-weighted magnetic resonance imaging (MRI) with relaxivity (r1,2) values outperforming currently-available clinical CAs by up to 16 times forﾠr1ﾠand 21 times forﾠr2.