Show simple item record

dc.contributor.authorSergi, Fabrizio
Pehlivan, Ali Utku
Fitle, Kyle
Nedley, Kathryn
Yozbatiran, Nuray
Francisco, Gerard E.
O’Malley, Marcia K.
dc.date.accessioned 2016-01-20T19:40:21Z
dc.date.available 2016-01-20T19:40:21Z
dc.date.issued 2015
dc.identifier.citation Sergi, Fabrizio, Pehlivan, Ali Utku, Fitle, Kyle, et al.. "Design of a parallel-group balanced controlled trial to test the effects of assist-as-needed robotic therapy." 2015 IEEE International Conference on Rehabilitation Robotics (ICORR), (2015) IEEE: 840-845. http://dx.doi.org/10.1109/ICORR.2015.7281307.
dc.identifier.urihttps://hdl.handle.net/1911/87886
dc.description.abstract In this methods paper, we report on the design of a clinical study testing the efficacy of a newly developed control scheme for robot-aided rehabilitation. To measure the value added by a new control scheme, we pursued a parallel-group controlled clinical study design. This approach enables comparing the effects of the novel scheme, based on the Assist-As-Needed (AAN) paradigm, with those of a less sophisticated, fixed gain, Subject-Triggered (ST) controller. We describe the steps followed in the design of this clinical study, including details on the implementation of the two control modes, and a power analysis to determine the required number of subjects to test a clinically significant difference hypothesis. Finally, we present a method for sequential group assignment with co-variates minimization, capable of guaranteeing a desired level of balance of prognostic factors in the two study groups, a crucial requisite for small-scale clinical studies in rehabilitation. To the best of our knowledge, the study presented is the first one testing, in a controlled fashion, the differential effects of a specific control mode in upper extremity rehabilitation after incomplete spinal cord injury.
dc.language.iso eng
dc.publisher IEEE
dc.rights This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by IEEE.
dc.title Design of a parallel-group balanced controlled trial to test the effects of assist-as-needed robotic therapy
dc.type Journal article
dc.contributor.funder TIRR Foundation
dc.citation.journalTitle 2015 IEEE International Conference on Rehabilitation Robotics (ICORR)
dc.contributor.org Mechatronics and Haptic Interfaces Laboratory
dc.type.dcmi Text
dc.identifier.doihttp://dx.doi.org/10.1109/ICORR.2015.7281307
dc.identifier.grantID 103-110 (TIRR Foundation)
dc.type.publication post-print
dc.citation.firstpage 840
dc.citation.lastpage 845


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record