Now showing items 109-111 of 111

    • Wee-1 Kinase Inhibition Overcomes Cisplatin Resistance Associated with High-RiskTP53ᅠMutations in Head and Neck Cancer through Mitotic Arrest Followed by Senescence 

      Osman, Abdullah A.; Monroe, Marcus M.; Alves, Marcus V. Ortega; Patel, Ameeta A.; Katsonis, Panagiotis; Fitzgerald, Alison L.; Neskey, David M.; Frederick, Mitchell J.; Woo, Sang Hyeok; Caulin, Carlos; Hsu, Teng-Kuei; McDonald, Thomas O.; Kimmel, Marek; Meyn, Raymond E.; Lichtarge, Olivier; Myers, Jeffrey N. (2015)
      Although cisplatin has played a role in "standard-of-care" multimodality therapy for patients with advanced squamous cell carcinoma of the head and neck (HNSCC), the rate of treatment failure remains particularly high for ...
    • WRDS Index Data Extraction Methodology 

      Dobelman, J.A.; Kang, H.B.; Park, S.W. (2014)
      This paper provides and validates an automatic procedure to generate accurate CRSP PERMNOs from Compustat GVKEYs for historical index constituents. We then validate the resulting PERMNO lists and examine some of the many ...
    • XMRF: an R package to fit Markov Networks to high-throughput genetics data 

      Wan, Ying-Wooi; Allen, Genevera I; Baker, Yulia; Yang, Eunho; Ravikumar, Pradeep; Anderson, Matthew; Liu, Zhandong (2016)
      Abstract Background Technological advances in medicine have led to a rapid proliferation of high-throughput “omics” data. Tools to mine this data and discover disrupted ...