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Optical spectroscopy and imaging systems for gynecological cancers: from Ultraviolet-C (UVC) to the Mid-infrared
Optical spectroscopy and imaging has proving to be of diagnostic relevance in many organ sites. We use fluorescence and FTIR spectroscopy to study gynecological organ sites and develop classification algorithms for cancer diagnosis. Ovarian cancer is the deadliest gynecological cancer. The American Cancer Society reports that for the year 20 I 0, ...
Inverse model for the extraction of biological parameters from ovarian tissue fluorescence spectra and multivariate classifiers for tissue diagnosis
We present an inverse model to decompose bulk fluorescence spectra and extract tissue biological parameters. By deconvolving the effects of absorption and scattering from measured spectra, we are able to extract the intrinsic contributions from cellular and stromal fluorophores. Ovarian fluorescence, acquired ex-vivo immediately upon removal from ...