Now showing items 26-45 of 139

    • Effects of Antibiotic Physicochemical Properties on Their Release Kinetics from Biodegradable Polymer Microparticles 

      Shah, Sarita R.; Henslee, Allan M.; Spicer, Patrick P.; Yokota, Shun; Petrichenko, Sophia; Allahabadi, Sachin; Bennett, George N.; Wong, Mark E.; Kasper, F. Kurtis; Mikos, Antonios G. (2014)
      Purpose: This study investigated the effects of the physicochemical properties of antibiotics on the morphology, loading efficiency, size, release kinetics, and antibiotic efficacy of loaded poly(DL-lactic-co-glycolic acid) ...
    • Effects of cellular parameters on the in vitro osteogenic potential of dual-gelling mesenchymal stem cell-laden hydrogels 

      Vo, Tiffany N.; Tabata, Yasuhiko; Mikos, Antonios G. (2016)
      This work investigated the effects of cellular encapsulation density and differentiation stage on the osteogenic capacity of injectable, dual physically and chemically gelling hydrogels comprised of thermogelling macromers ...
    • Efficient synthesis of L-lactic acid from glycerol by metabolically engineered Escherichia coli 

      Mazumdar, Suman; Blankschien, Matthew D; Clomburg, James M; Gonzalez, Ramon (2013)
      Due to its abundance and low-price, glycerol has become an attractive carbon source for the industrial production of value-added fuels and chemicals. This work reports the engineering of E. coli for the efficient conversion ...
    • Endoplasmic Reticulum-Associated rht-PA Processing in CHO Cells: Influence of Mild Hypothermia and Specific Growth Rates in Batch and Chemostat Cultures 

      Vergara, Mauricio; Berrios, Julio; Martínez, Irene; Díaz-Barrera, Alvaro; Acevedo, Cristian; Reyes, Juan G.; Gonzalez, Ramon; Altamirano, Claudia (2015)
      Background: Chinese hamster ovary (CHO) cells are the main host for producing recombinant proteins with human therapeutic applications mainly because of their capability to perform proper folding and glycosylation processes. ...
    • Examining Asphaltene Solubility on Deposition in Model Porous Media 

      Lin, Yu-Jiun; He, Peng; Tavakkoli, Mohammad; Mathew, Nevin Thunduvila; Fatt, Yap Yit; Chai, John C.; Goharzadeh, Afshin; Vargas, Francisco M.; Biswal, Sibani Lisa (2016)
      Asphaltenes are known to cause severe flow assurance problems in the near-wellbore region of oil reservoirs. Understanding the mechanism of asphaltene deposition in porous media is of great significance for the development ...
    • Experimental realization of crossover in shape and director field of nematic tactoids 

      Jamali, Vida; Behabtu, Natnael; Senyuk, Bohdan; Lee, J. Alex; Smalyukh, Ivan I.; van der Schoot, Paul; Pasquali, Matteo (2015)
      Spindle-shaped nematic droplets (tactoids) form in solutions of rod-like molecules at the onset of the liquid crystalline phase. Their unique shape and internal structure result from the interplay of the elastic deformation ...
    • Fabrication and characterization of multiscale electrospun scaffolds for cartilage regeneration 

      Levorson, Erica J.; Sreerekha, Perumcherry Raman; Chennazhi, Krishna Prasad; Kasper, F. Kurtis; Nair, Shantikumar V.; Mikos, Antonios G. (2013)
      Recently, scaffolds for tissue regeneration purposes have been observed to utilize nanoscale features in an effort to reap the cellular benefits of scaffold features resembling extracellular matrix (ECM) components. However, ...
    • Facile Graphene Oxide Preparation by Microwave-Assisted Acid Method 

      Viana, Marcelo M.; Lima, Meiriane C.F.S.; Forsythe, Jerimiah C.; Gangoli, Varun S.; Cho, Minjung; Cheng, Yinhong; Silva, Glaura G.; Wong, Michael S.; Caliman, Vinicius (2015)
      Few-layered graphene oxide (GO) was prepared using a fast and energy-saving method by microwave-assisted acid technique. The oxygenated groups existing on the GO surface were determined using UV-Vis, X-ray photoelectron ...
    • From strings to coils: Rotational dynamics of DNA-linked colloidal chains 

      Kuei, Steve; Garza, Burke; Biswal, Sibani Lisa (2017)
      We investigate the dynamical behavior of deformable filaments experimentally using a tunable model system consisting of linked paramagnetic colloidal particles, where the persistence length lp, the contour length lc, and ...
    • Gelatin carriers for drug and cell delivery in tissue engineering 

      Santoro, Marco; Tatara, Alexander M.; Mikos, Antonios G. (2014)
      The ability of gelatin to form complexes with different drugs has been investigated for controlled release applications. Gelatin parameters, such as crosslinking density and isoelectric point, have been tuned in order to ...
    • Genetic and Chemical Activation of TFEB Mediates Clearance of Aggregated α-Synuclein 

      Kilpatrick, Kiri; Zeng, Yimeng; Hancock, Tommy; Segatori, Laura (2015)
      Aggregation of α-synuclein (α-syn) is associated with the development of a number of neurodegenerative diseases, including Parkinson’s disease (PD). The formation of α-syn aggregates results from aberrant accumulation of ...
    • High efficiency carbon nanotube thread antennas 

      Bengio, E. Amram; Senic, Damir; Taylor, Lauren W.; Tsentalovich, Dmitri E.; Chen, Peiyu; Holloway, Christopher L.; Babakhani, Aydin; Long, Christian J.; Novotny, David R.; Booth, James C.; Orloff, Nathan D.; Pasquali, Matteo (2017)
      Although previous research has explored the underlying theory of high-frequency behavior of carbon nanotubes (CNTs) and CNT bundles for antennas, there is a gap in the literature for direct experimental measurements of ...
    • High pressure measurements and molecular modeling of the water content of acid gas containing mixtures 

      Fouad, Wael A.; Yarrison, Matt; Song, Kyoo Y.; Cox, Kenneth R.; Chapman, Walter G. (2015)
      Water content of three carbon dioxide containing natural gas mixtures in equilibrium with an aqueous phase was measured using a dynamic saturation method. Measurements were performed up to high temperatures (477.6 K = 400°F) ...
    • High-Ampacity Power Cables of Tightly-Packed and Aligned Carbon Nanotubes 

      Wang, Xuan; Behabtu, Natnael; Young, Colin C.; Tsentalovich, Dmitri E.; Pasquali, Matteo; Kono, Junichiro (2014)
      The current-carrying capacity (CCC), or ampacity, of highly-conductive, light, and strong carbon nanotube (CNT) fibers is characterized by measuring their failure current density (FCD) and continuous current rating (CCR) ...
    • Highly Flexible Self-Assembled V2O5 Cathodes Enabled by Conducting Diblock Copolymers 

      An, Hyosung; Mike, Jared; Smith, Kendall A.; Swank, Lisa; Lin, Yen-Hao; Pesek, Stacy L.; Verduzco, Rafael; Lutkenhaus, Jodie L. (2015)
      Mechanically robust battery electrodes are desired for applications in wearable devices, flexible displays, and structural energy and power. In this regard, the challenge is to balance mechanical and electrochemical ...
    • HSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancer 

      Mondal, Susmita; Roy, Debarshi; Camacho-Pereira, Juliana; Khurana, Ashwani; Chini, Eduardo; Yang, Lifeng; Baddour, Joelle; Stilles, Katherine; Padmabandu, Seth; Leung, Sam; Kalloger, Steve; Gilks, Blake; Lowe, Val; Dierks, Thomas; Hammond, Edward; Dredge, Keith; Nagrath, Deepak; Shridhar, Viji (2015)
      Warburg effect has emerged as a potential hallmark of many cancers. However, the molecular mechanisms that led to this metabolic state of aerobic glycolysis, particularly in ovarian cancer (OVCA) have not been completely ...
    • Human Omental-Derived Adipose Stem Cells Increase Ovarian Cancer Proliferation, Migration, and Chemoresistance 

      Nowicka, Aleksandra; Marini, Frank C.; Solley, Travis N.; Elizondo, Paula B.; Zhang, Yan; Sharp, Hadley J.; Broaddus, Russell; Kolonin, Mikhail; Mok, Samuel C.; Thompson, Melissa S.; Woodward, Wendy A.; Lu, Karen; Salimian, Bahar; Nagrath, Deepak; Klopp, Ann H. (2013)
      Objectives: Adipose tissue contains a population of multipotent adipose stem cells (ASCs) that form tumor stroma and can promote tumor progression. Given the high rate of ovarian cancer metastasis to the omental adipose, ...
    • Hybrid graphene metasurfaces for high-speed mid-infrared light modulation and single-pixel imaging 

      Zeng, Beibei; Huang, Zhiqin; Singh, Akhilesh; Yao, Yu; Azad, Abul K.; Mohite, Aditya D.; Taylor, Antoinette J.; Smith, David R.; Chen, Hou-Tong (2018)
      During the past decades, major advances have been made in both the generation and detection of infrared light; however, its efficient wavefront manipulation and information processing still encounter great challenges. ...
    • Hydrophobic and hydrophilic interactions in aqueous mixtures of alcohols at a hydrophobic surface 

      Ballal, Deepti; Chapman, Walter G. (2013)
      Aqueous solutions of alcohols are interesting because of their anomalous behavior that is believed to be due to the molecular structuring of water and alcohol around each other in solution. The interfacial structuring and ...
    • The impact of lithologic heterogeneity and focused fluid flow upon gas hydrate distribution in marine sediments 

      Chatterjee, Sayantan; Bhatnagar, Gaurav; Dugan, Brandon; Dickens, Gerald R.; Chapman, Walter G.; Hirasaki, George J. (2014)
      Gas hydrate and free gas accumulation in heterogeneous marine sediment is simulated using a two-dimensional (2-D) numerical model that accounts for mass transfer over geological timescales. The model extends a previously ...