Now showing items 1-20 of 3897

    • An omnipresent diversity and variability in the chemical composition of atmospheric functionalized organic aerosol 

      Ditto, Jenna C.; Barnes, Emily B.; Khare, Peeyush; Takeuchi, Masayuki; Joo, Taekyu; Bui, Alexander A.T.; Lee-Taylor, Julia; Eris, Gamze; Chen, Yunle; Aumont, Bernard; Jimenez, Jose L.; Ng, Nga Lee; Griffin, Robert J.; Gentner, Drew R. (2018)
      The atmospheric evolution of organic compounds encompasses many thousands of compounds with varying volatility, polarity, and water solubility. The molecular-level chemical composition of this mixture plays a major, yet ...
    • The effect of plate design, bridging span, and fracture healing on the performance of high tibial osteotomy plates: An experimental and finite element study 

      MacLeod, A.R.; Serrancoli, G.; Fregly, B.J.; Toms, A.D.; Gill, H.S. (2018)
      Objectives: Opening wedge high tibial osteotomy (HTO) is an established surgical procedure for the treatment of early-stage knee arthritis. Other than infection, the majority of complications are related to mechanical ...
    • The role of interventions in the cancer evolution–an evolutionary games approach 

      Swierniak, A.; Krzeslak, M.; Borys, D.; Kimmel, M. (2019)
      We propose to endow evolutionary game models with changes of the phenotypes adjustment during the transient generations performed by the parameters in the payo matrix which determine the fitness resulting from di erent ...
    • Phenotypic Plasticity, Bet-Hedging, and Androgen Independence in Prostate Cancer: Role of Non-Genetic Heterogeneity 

      Jolly, Mohit Kumar; Kulkarni, Prakash; Weninger, Keith; Orban, John; Levine, Herbert (2018)
      It is well known that genetic mutations can drive drug resistance and lead to tumor relapse. Here, we focus on alternate mechanisms-those without mutations, such as phenotypic plasticity and stochastic cell-to-cell variability ...
    • Biophysics of object segmentation in a collision-detecting neuron 

      Dewell, Richard Burkett; Gabbiani, Fabrizio (2018)
      Adaptive collision avoidance behaviours require accurate detection of complex spatiotemporal properties of an object approaching in an animal's natural, three-dimensional environment. Within the locust, the lobula giant ...
    • Surfactant-assisted individualization and dispersion of boron nitride nanotubes 

      McWilliams, Ashleigh D. Smith; Reyes, Carlos A. de los; Liberman, Lucy; Ergülen, Selin; Talmon, Yeshayahu; Pasquali, Matteo; A. Martí, Angel (2019)
      Boron nitride nanotubes (BNNTs) belong to a novel class of material with useful thermal, electronic and optical properties. However, the study and the development of applications of this material requires the formation of ...
    • Spatially-Resolved Photoluminescence of Monolayer MoS2 under Controlled Environment for Ambient Optoelectronic Applications 

      Birmingham, Blake; Yuan, Jiangtan; Filez, Matthias; Fu, Donglong; Hu, Jonathan; Lou, Jun; Scully, Marlan O.; Weckhuysen, Bert M.; Zhang, Zhenrong (2018)
      Monolayer (ML) MoS2 has become a very promising two-dimensional material for photorelated applications, potentially serving as the basis for an ultrathin photodetector, switching device, or transistors because of its strong ...
    • Carbon Nanotubes and Related Nanomaterials: Critical Advances and Challenges for Synthesis toward Mainstream Commercial Applications 

      Rao, Rahul; Pint, Cary L.; Islam, Ahmad E.; Weatherup, Robert S.; Hofmann, Stephan; Meshot, Eric R.; Wu, Fanqi; Zhou, Chongwu; Dee, Nicholas; Amama, Placidus B.; Carpena-Nuñez, Jennifer; Shi, Wenbo; Plata, Desiree L.; Penev, Evgeni S.; Yakobson, Boris I.; Balbuena, Perla B.; Bichara, Christophe; Futaba, Don N.; Noda, Suguru; Shin, Homin; Kim, Keun Su; Simard, Benoit; Mirri, Francesca; Pasquali, Matteo; Fornasiero, Francesco; Kauppinen, Esko I.; Arnold, Michael; Cola, Baratunde A.; Nikolaev, Pavel; Arepalli, Sivaram; Cheng, Hui-Ming; Zakharov, Dmitri N.; Stach, Eric A.; Zhang, Jin; Wei, Fei; Terrones, Mauricio; Geohegan, David B.; Maruyama, Benji; Maruyama, Shigeo; Li, Yan; Adams, W. Wade; Hart, A. John (2018)
      Advances in the synthesis and scalable manufacturing of single-walled carbon nanotubes (SWCNTs) remain critical to realizing many important commercial applications. Here we review recent breakthroughs in the synthesis of ...
    • Metallic nanoparticles for cancer immunotherapy 

      Evans, Emily Reiser; Bugga, Pallavi; Asthana, Vishwaratn; Drezek, Rebekah (2018)
      Cancer immunotherapy, or the utilization of the body’s immune system to attack tumor cells, has gained prominence over the past few decades as a viable cancer treatment strategy. Recently approved immunotherapeutics have ...
    • MEXIT: Maximal un-coupling times for stochastic processes 

      Ernst, Philip A.; Kendall, Wilfrid S.; Roberts, Gareth O.; Rosenthal, Jeffrey S. (2019)
      Classical coupling constructions arrange for copies of the same Markov process started at two different initial states to become equal as soon as possible. In this paper, we consider an alternative coupling framework in ...
    • A Self-Deleting AAV-CRISPR System for In Vivo Genome Editing 

      Li, Ang; Lee, Ciaran M.; Hurley, Ayrea E.; Jarrett, Kelsey E.; De Giorgi, Marco; Lu, Weiqi; Balderrama, Karol S.; Doerfler, Alexandria M.; Deshmukh, Harshavardhan; Ray, Anirban; Bao, Gang; Lagor, William R. (2019)
      Adeno-associated viral (AAV) vectors packaging the CRISPR-Cas9 system (AAV-CRISPR) can efficiently modify disease-relevant genes in somatic tissues with high efficiency. AAV vectors are a preferred delivery vehicle for ...
    • Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer 

      Jolly, Mohit Kumar; Preca, Bogdan-Tiberius; Tripathi, Satyendra C.; Jia, Dongya; George, Jason T.; Hanash, Samir M.; Brabletz, Thomas; Stemmler, Marc P.; Maurer, Jochen; Levine, Herbert (2018)
      Aberrant activation of epithelial-mesenchymal transition (EMT) in carcinoma cells contributes to increased migration and invasion, metastasis, drug resistance, and tumor-initiating capacity. EMT is not always a binary ...
    • A finite element model for magnetohydrodynamic squeeze-film flows 

      Wagner, Jordan R.; Higgs, C. Fred III (2018)
      A computational model is developed to analyze magnetohydrodynamic (MHD) squeeze-film flows featuring an electrically conducting fluid subjected to imposed magnetic and electric fields. The model is based on the so-called ...
    • Quantitative comparison of adaptive sampling methods for protein dynamics 

      Hruska, Eugen; Abella, Jayvee R.; Nüske, Feliks; Kavraki, Lydia E.; Clementi, Cecilia (2018)
      Adaptive sampling methods, often used in combination with Markov state models, are becoming increasingly popular for speeding up rare events in simulation such as molecular dynamics (MD) without biasing the system dynamics. ...
    • High photoresponse of individual WS2 nanowire-nanoflake hybrid materials 

      Asres, Georgies Alene; Järvinen, Topias; Lorite, Gabriela S.; Mohl, Melinda; Pitkänen, Olli; Dombovari, Aron; Tóth, Geza; Spetz, Anita Lloyd; Vajtai, Robert; Ajayan, Pulickel M.; Lei, Sidong; Talapatra, Saikat; Kordas, Krisztian (2018)
      van der Waals solids have been recognized as highly photosensitive materials that compete conventional Si and compound semiconductor based devices. While 2-dimensional nanosheets of single and multiple layers and 1-dimensional ...
    • Isotropic Seebeck coefficient of aligned single-wall carbon nanotube films 

      Fukuhara, Kengo; Ichinose, Yota; Nishidome, Hiroyuki; Yomogida, Yohei; Katsutani, Fumiya; Komatsu, Natsumi; Gao, Weilu; Kono, Junichiro; Yanagi, Kazuhiro (2018)
      How the morphology of a macroscopic assembly of nanoobjects affects its properties is a long-standing question in nanomaterials science and engineering. Here, we examine how the thermoelectric properties of a flexible thin ...
    • Long distance, distributed gas sensing based on micro-nano fiber evanescent wave quartz-enhanced photoacoustic spectroscopy 

      He, Ying; Ma, Yufei; Tong, Yao; Yu, Xin; Peng, Zhenfang; Gao, Jing; Tittel, Frank K. (2017)
      A long distance, distributed gas sensing using the micro-nano fiber evanescent wave (FEW) quartz enhanced photoacoustic spectroscopy technique was demonstrated. Such a sensor scheme has the advantages of higher detection ...
    • Molecular search with conformational change: One-dimensional discrete-state stochastic model 

      Shin, Jaeoh; Kolomeisky, Anatoly B. (2018)
      Molecular search phenomena are observed in a variety of chemical and biological systems. During the search, the participating particles frequently move in complex inhomogeneous environments with random transitions between ...
    • Rho-Associated Coiled-Coil Kinase (ROCK) in Molecular Regulation of Angiogenesis 

      Liu, Jing; Wada, Youichiro; Katsura, Mari; Tozawa, Hideto; Erwin, Nicholas; Kapron, Carolyn M; Bao, Gang; Liu, Ju (2018)
      Identified as a major downstream effector of the small GTPase RhoA, Rho-associated coiled-coil kinase (ROCK) is a versatile regulator of multiple cellular processes. Angiogenesis, the process of generating new capillaries ...
    • Performance Enhancement of Methane Detection Using a Novel Self-Adaptive Mid-Infrared Absorption Spectroscopy Technique 

      Song, Fang; Zheng, Chuantao; Yan, Wanhong; Ye, Wei Lin; Zhang, Yu; Wang, Yiding; Tittel, Frank K. (2018)
      An electrical-domain self-adaptive mid-infrared absorption spectroscopy for methane detection based on an interband cascade laser was demonstrated. By adding noise into the laser drive signal, denoising and sensing ...