Now showing items 3498-3517 of 3957

    • Synthetic biodegradable hydrogel delivery of demineralized bone matrix for bone augmentation in a rat model 

      Kinard, Lucas A.; Dahlin, Rebecca L.; Lam, Johnny; Lu, Steven; Lee, Esther J.; Kasper, F. Kurtis; Mikos, Antonios G. (2014)
      There exists a strong clinical need for a more capable and robust method to achieve bone augmentation, and a system with fine-tuned delivery of demineralized bone matrix (DBM) has the potential to meet that need. As such, ...
    • Synthetic Biology and the Gut Microbiome 

      Dou, Jennifer; Bennett, Matthew R. (2018)
      The gut microbiome plays a crucial role in maintaining human health. Functions performed by gastrointestinal microbes range from regulating metabolism to modulating immune and nervous system development. Scientists have ...
    • Synthetic Biology Open Language Visual (SBOL Visual) Version 2.0 

      Cox, Robert Sidney; Madsen, Curtis; McLaughlin, James; Nguyen, Tramy; Roehner, Nicholas; Bartley, Bryan; Bhatia, Swapnil; Bissell, Mike; Clancy, Kevin; Gorochowski, Thomas; Grünberg, Raik; Luna, Augustin; Le Novère, Nicolas; Pocock, Matthew; Sauro, Herbert; Sexton, John T.; Stan, Guy-Bart; Tabor, Jeffrey J.; Voigt, Christopher A.; Zundel, Zach; Myers, Chris; Beal, Jacob; Wipat, Anil (2018)
      People who are engineering biological organisms often find it useful to communicate in diagrams, both about the structure of the nucleic acid sequences that they are engineering and about the functional relationships between ...
    • A Synthetic Matrix with Independently Tunable Biochemistry and Mechanical Properties to Study Epithelial Morphogenesis and EMT in a Lung Adenocarcinoma Model 

      Gill, Bartley J.; Gibbons, Don L.; Roudsari, Laila C.; Saik, Jennifer E.; Rizvi, Zain H.; Roybal, Jonathon D.; Kurie, Jonathan M.; West, Jennifer L. (2012)
      Better understanding of the biophysical and biochemical cues of the tumor extracellular matrix environment that influence metastasis may have important implications for new cancer therapeutics. Initial exploration into ...
    • Systematic Calibration of Model Parameters Based on Large-Scale Experiments on Hybrid Masonry Walls 

      Gao, Zhenjia; Stanciulescu, Ilinca (2016)
      Hybrid masonry is a relatively new type of structural system that benefits from the ductility and ease of construction of steel frames and from the in-plane strength and stiffness of reinforced masonry panels. Finite element ...
    • Systematic Construction of Higher Order Bases for the Finite Element Analysis of Multiscale Elliptic Problems 

      Soghrati, Soheil; Stanciulescu, Ilinca (2013)
      We introduce a new approach to deriving higher order basis functions implemented in the Multiscale Finite Element Method (MsFEM) for elliptic problems. MsFEM relies on capturing small scale features of the system through ...
    • Systematically probing the bottom-up synthesis of AuPAMAM conjugates for enhanced transfection efficiency 

      Figueroa, Elizabeth R; Stephen Yan, J.; Chamberlain-Simon, Nicolette K; Lin, Adam Y; Foster, Aaron E; Drezek, Rebekah A (2016)
      Abstract Background Gold nanoparticles (AuNPs) have shown great promise as scaffolds for gene therapy vectors due to their attractive physiochemical properties which include ...
    • Systems approaches for synthetic biology: a pathway toward mammalian design 

      Rekhi, Rahul; Qutub, Amina A. (2013)
      We review methods of understanding cellular interactions through computation in order to guide the synthetic design of mammalian cells for translational applications, such as regenerative medicine and cancer therapies. In ...
    • A Systolic VLSI Architecture for Complex SVD 

      Hemkumar, Nariankadu D.; Cavallaro, Joseph R. (1992-05-20)
      A systolic algorithm for the SVD of arbitrary complex matrices, based on the cyclic Jacobi method with "parallel ordering" is presented. A novel two-step, two-sided unitary transformation scheme, tailored to the use of ...
    • Syzygies for translational surfaces 

      Wang, Haohao; Goldman, Ron (2018)
      A translational surface is a rational tensor product surface generated from two rational space curves by translating one curve along the other curve. Translational surfaces are invariant under rigid motions: translating ...
    • T Cell Repertoire Diversity Is Decreased in Type 1 Diabetes Patients 

      Tong, Yin; Li, Zhoufang; Zhang, Hua; Xia, Ligang; Zhang, Meng; Xu, Ying; Wang, Zhanhui; Deem, Michael W.; Sun, Xiaojuan; He, Jiankui (2016)
      Type 1 diabetes mellitus (T1D) is an immune-mediated disease. The autoreactive T cells in T1D patients attack and destroy their own pancreatic cells. In order to systematically investigate the potential autoreactive T cell ...
    • Tagged Architecture and the Semantics Programming Languages: Extensible Types 

      Feustel, Edward A. (1975-11-20)
      This research note suggests that before we design hardware or software for the task of problem solving, we re-evaluate the task of problem solving in terms of the linguistic constituents which will be required and the ...
    • Tagged Architectures and Protection: Message Systems 

      Feustel, Edward A. (1975-10-20)
      Recent work in extensible programming languages and operating systems by Redell, Lampson, Hewitt, and others coupled with developments in distributed computer systems motivates a study in models of the implementation of ...
    • Taguchi and Robust Optimization 

      Trosset, Michael W. (1996-10)
      This report is intended to facilitate dialogue between engineers and optimizers about the efficiency of Taguchi methods for robust design, especially in the context of design by computer simulation. Three approaches to ...
    • Tailoring the Attraction of Polymers toward Surfaces 

      Stein, Gila E.; Laws, Travis S.; Verduzco, Rafael (2019)
      In polymer blends and block copolymers, one constituent (or segment type) is often enriched at the surface. This enrichment has important consequences for a variety of surface functions, including wettability, adhesive ...
    • Taking TrackBack Back (from Spam) 

      Gerecht, Paul; McDonald, Rob; Sandler, Dan; Wallach, Dan S. (2006-05-19)
      The TrackBack protocol, conceived as a way to automatically link together web sites which reference one another, has become a new vector for spammers wishing to divert web surfers to their sites. A site which supports ...
    • TAP Channel Measurement: Fundamentals, Goals, and Plans 

      Steger, Christopher (2004-05-01)
      Before we can realize the potential of the TAP (Transit Access Point) project, we must first understand the channel in which we will operate. Specifically, very little information exists on the characteristics of elevated ...
    • Targeting pancreatic cancer with magneto-fluorescent theranostic gold nanoshells 

      Chen, Wenxue; Ayala-Orozco, Ciceron; Biswal, Nrusingh C.; Perez-Torres, Carlos; Bartels, Marc; Bardhan, Rizia; Stinnet, Gary; Liu, Xian-De; Ji, Baoan; Deorukhkar, Amit; Brown, Lisa V.; Guha, Sushovan; Pautler, Robia G.; Krishnan, Sunil; Halas, Naomi J.; Joshi, Amit (2014)
      Aim: We report a magneto-fluorescent theranostic nanocomplex targeted to neutrophil gelatinase-associated lipocalin (NGAL) for imaging and therapy of pancreatic cancer. Materials & methods: Gold nanoshells resonant at 810 ...
    • Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 6 (STAT6) with Cell-Permeable, Phosphatase-Stable Phosphopeptide Mimics Potently Inhibits Tyr641 Phosphorylation and Transcriptional Activity 

      Mandal, Pijus K.; Morlacchi, Pietro; Knight, J. Morgan; Link, Todd M.; Lee, Gilbert R. IV; Nurieva, Roza; Singh, Divyendu; Dhanik, Ankur; Kavraki, Lydia; Corry, David B.; Ladbury, John E.; McMurray, John S. (2015)
      Signal transducer and activator of transcription 6 (STAT6) transmits signals from cytokines IL-4 and IL-13 and is activated in allergic airway disease. We are developing phosphopeptide mimetics targeting the SH2 domain of ...
    • Task Partitioning Wireless Base-station Receiver Algorithms on Multiple DSPs and FPGAs 

      Rajagopal, Sridhar; Jones, Bryan Allen; Cavallaro, Joseph R. (2000-10-20)
      This paper presents a multiprocessor solution to meet real-time requirements of implementing advanced algorithms for multiuser channel estimation and detection for third and fourth generation wireless base-station receivers. ...