Now showing items 1138-1157 of 2899

    • Host-Guest Self-assembly in Block Copolymer Blends 

      Park, Woon Ik; Kim, YongJoo; Jeong, Jae Won; Kim, Kyungho; Yoo, Jung-Keun; Hur, Yoon Hyung; Kim, Jong Min; Thomas, Edwin L.; Alexander-Katz, Alfredo; Jung, Yeon Sik (2013)
      Ultrafine, uniform nanostructures with excellent functionalities can be formed by self-assembly of block copolymer (BCP) thin films. However, extension of their geometric variability is not straightforward due to their ...
    • Hot embossed polyethylene through-hole chips for bead-based microfluidicdevices 

      Chou, Jie; Du, Nan; Ou, Tina; Floriano, Pierre N.; Christodoulides, Nicolaos; McDevitt, John T. (2013)
      Over the past decade, there has been a growth of interest in the translation of microfluidic systems into real-world clinical practice, especially for use in point-of-care or near patient settings. While initial fabrication ...
    • How Can Single Sensory Neurons Predict Behavior? 

      Pitkow, Xaq; Liu, Sheng; Angelaki, Dora E.; DeAngelis, Gregory C.; Pouget, Alex (2015)
      Singleᅠsensory neuronsᅠcan be surprisingly predictive of behavior in discrimination tasks. We propose this isᅠpossible because sensory information extracted from neural populations is severely restricted, either by ...
    • How Quickly Can We Approach Channel Capacity? 

      Baron, Dror; Khojastepour, Mohammad; Baraniuk, Richard G. (2004-11-01)
      Recent progress in code design has made it crucial to understand how quickly communication systems can approach their limits. To address this issue for the channel capacity C, we define the nonasymptotic capacity C/sub ...
    • How the interplay between mechanical and non-mechanical interactions affects multiple kinesin dynamics 

      Uppulury, Karthik; Efremov, Artem K.; Driver, Jonathan W.; Jamison, D. Kenneth; Diehl, Michael R.; Kolomeisky, Anatoly B. (2012)
      Intracellular transport is supported by enzymes called motor proteins that are often coupled to the same cargo and function collectively. Recent experiments and theoretical advances have been able to explain certain behaviors ...
    • How To Build an Undervoting Machine: Lessons from an Alternative Ballot Design 

      Greene, Kristen K.; Byrne, Michael D.; Goggin, Stephen N. (2013-08)
      Despite the importance of usability in ensuring election integrity, it remains an under-studied aspect of voting systems. Voting computers (a.k.a. DREs) offer the opportunity to present ballots to voters in novel ways, yet ...
    • How to train your microbe: methods for dynamically characterizing gene networks 

      Castillo-Hair, Sebastian M.; Igoshin, Oleg A.; Tabor, Jeffrey J. (2015)
      Gene networks regulate biological processes dynamically. However, researchers have largely relied upon static perturbations, such as growth media variations and gene knockouts, to elucidate gene network structure and ...
    • HPCTOOLKIT: Tools for performance analysis of optimized parallel programs 

      Adhianto, L.; Banerjee, S.; Fagan, M.; Krentel, M.; Marin, G.; Mellor-Crummey, J.; Tallent, N. R. (2008-10-03)
      HPCTOOLKIT is an integrated suite of tools that supports measurement, analysis, attribution, and presentation of application performance for both sequential and parallel programs. HPCTOOLKIT can pinpoint and quantify ...
    • HSulf-1 deficiency dictates a metabolic reprograming of glycolysis and TCA cycle in ovarian cancer 

      Mondal, Susmita; Roy, Debarshi; Camacho-Pereira, Juliana; Khurana, Ashwani; Chini, Eduardo; Yang, Lifeng; Baddour, Joelle; Stilles, Katherine; Padmabandu, Seth; Leung, Sam; Kalloger, Steve; Gilks, Blake; Lowe, Val; Dierks, Thomas; Hammond, Edward; Dredge, Keith; Nagrath, Deepak; Shridhar, Viji (2015)
      Warburg effect has emerged as a potential hallmark of many cancers. However, the molecular mechanisms that led to this metabolic state of aerobic glycolysis, particularly in ovarian cancer (OVCA) have not been completely ...
    • Human Omental-Derived Adipose Stem Cells Increase Ovarian Cancer Proliferation, Migration, and Chemoresistance 

      Nowicka, Aleksandra; Marini, Frank C.; Solley, Travis N.; Elizondo, Paula B.; Zhang, Yan; Sharp, Hadley J.; Broaddus, Russell; Kolonin, Mikhail; Mok, Samuel C.; Thompson, Melissa S.; Woodward, Wendy A.; Lu, Karen; Salimian, Bahar; Nagrath, Deepak; Klopp, Ann H. (2013)
      Objectives: Adipose tissue contains a population of multipotent adipose stem cells (ASCs) that form tumor stroma and can promote tumor progression. Given the high rate of ovarian cancer metastasis to the omental adipose, ...
    • Hyaluronan (HA) Interacting Proteins RHAMM and Hyaluronidase Impact Prostate Cancer Cell Behavior and Invadopodia Formation in 3D HA-Based Hydrogels 

      Gurski, Lisa A.; Xu, Xian; Labrada, Lyana N.; Nguyen, Ngoc T.; Xiao, Longxi; van Golen, Kenneth L.; Jia, Xinqiao; Farach-Carson, Mary C. (2012)
      To study the individual functions of hyaluronan interacting proteins in prostate cancer (PCa) motility through connective tissues, we developed a novel three-dimensional (3D) hyaluronic acid (HA) hydrogel assay that provides ...
    • Hyaluronan Hydrogels for a Biomimetic Spongiosa Layer of Tissue Engineered Heart Valve Scaffolds 

      Puperi, Daniel S.; O’Connell, Ronan W.; Punske, Zoe E.; Wu, Yan; West, Jennifer L.; Grande-Allen, K. Jane (2016)
      Advanced tissue engineered heart valves must be constructed from multiple materials to better mimic the heterogeneity found in the native valve. The trilayered structure of aortic valves provides the ability to open and ...
    • Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves 

      Stephens, Elizabeth H.; Saltarrelli, Jerome G. Jr.; Balaoing, Liezl R.; Baggett, L. Scott; Nandi, Indrajit; Anderson, Kristin M.; Morrisett, Joel D.; Reardon, Michael J.; Simpson, Melanie A.; Weigel, Paul H.; Olmsted-Davis, Elizabeth A.; Davis, Alan R.; Grande-Allen, K. Jane (2012)
      The calcification process in aortic stenosis has garnered considerable interest but only limited investigation into selected signaling pathways. This study investigated mechanisms related to hypoxia, hyaluronan homeostasis, ...
    • Hyaluronan: A simple polysaccharide with diverse biological functions 

      Dicker, Kevin T.; Gurski, Lisa A.; Pradhan-Bhatt, Swati; Witt, Robert L.; Farach-Carson, Mary C.; Jia, Xinqiao (2014)
      Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid and N-acetyl-d-glucosamine. It is evolutionarily conserved and abundantly expressed in the extracellular matrix (ECM), on the cell ...
    • Hybrid 2D Nanomaterials as Dual-mode Contrast Agents in Cellular Imaging 

      Narayanan, Tharangattu N.; Gupta, Bipin K.; Vithayathil, Sajna A.; Aburto, Rebeca R.; Mani, Sendurai A.; Taha-Tijerina, Jaime; Xie, Bin; Kaipparettu, Benny A.; Torti, Suzy V.; Ajayan, Pulickel M. (2012)
    • Hybrid Dixon Resultants 

      Chionh, Eng-Wee; Goldman, Ronald; Zhang, Ming (1998-05-13)
      Dixon [1908] describes three distinct homogeneous determinant representations for the resultant of three bivariate polynomials of bidegree(m,n). These Dixon resultants are the determinants of matrices of orders 6mn, 3mn ...
    • Hybrid Linear / Bilinear Time-Scale Analysis 

      Pasquier, Martin; Goncalves, Paulo; Baraniuk, Richard G. (1999-01-01)
      We introduce a new method for the time-scale analysis of non-stationary signals. Our work leverages the success of the "time-frequency distribution series / cross-term deleted representations" into the time-scale domain ...
    • Hybrid Linear-Iterative Detection Algorithms for MIMO CDMA 

      Muharemovic, Tarik; Onggosanusi, Eko; Dabak, Anand; Aazhang, Behnaam (2002-05-20)
      We assume a CDMA downlink multiuser scenario, where the base station is equipped with multiple transmit antennas, and each user has multiple receive antennas. For this setup we propose a new, computationally effective MIMO ...
    • Hybrid Linear/Bilinear Time-Scale Analysis 

      Pasquier, Martin; Goncalves, Paulo; Baraniuk, Richard G. (1996-06-01)
      We introduce a new method for the time-scale analysis of nonstationary signals. Our work leverages the success of the â time-frequency distribution series/cross-term deleted representationsâ into the time-scale domain ...
    • Hybrid Linear/Quadratic Time-Frequency Attributes 

      Baraniuk, Richard G.; Coates, Mark J.; Steeghs, Philippe (2001-04-01)
      We present an efficient method for robustly calculating time-frequency attributes of a signal, including instantaneous mean frequency, bandwidth, kurtosis, and other moments. Most current attribute estimation techniques ...