Now showing items 1-4 of 4
A study of the fluid mechanics and the cultivation of mammalian cells in a magnetically stabilized fluidized bed bioreactor
The culture of anchorage dependent mammalian cells on microcarrier offers an attractive avenue for achieving high productivity of therapeutic and diagnostic proteins in bioreactors. Reducing production costs require high ...
Catharanthus roseus as a model system for the study of the phytoremediation of TNT
C. roseus hairy roots cultures were employed to prove the ability of plants to take up and transform TNT in the absence of microbes. Mass balances performed with 14C-TNT showed that the TNT was being taken up and transformed ...
Establishment, cultivation and optimization of hairy roots of Catharanthus roseus for the synthesis of indole alkaloids
"Hairy" roots hold the potential for economically feasible biotechnological routes to the controlled biosynthesis of complex, plant-derived, 'natural' molecules. A novel transgenic root system of the tropical plant ...
Effect of laminar shear stress on gene regulation, protein synthesis, and protein secretion by cultured human endothelial cells
To test the hypothesis that wall shear stress generated by blood flow may regulate endothelial cell expression of blood clot dissolving proteins or vasoactive proteins, an in vitro perfusion system was used to expose human ...