Now showing items 1-4 of 4
Insights into peroxisome matrix protein import and IBA metabolism through analysis of IBA-response mutants
Peroxisomes are single membrane-bound organelles that function to compartmentalize certain metabolic reactions critical to plant and animal development. I have studied peroxisomal processes in the model plant Arabidopsis ...
The Saccharomyces cerecisiae hsp70 escort protein Hep1 exhibits cross-reactivity with a non-cognate chaperone
Genetic studies have provided evidence that the hsp70 escort protein Hep1 is essential for maintaining the solubility of the mitochondrial chaperones Ssc1 and Ssq1 in Saccharomyces cerevisiae. However, little is known about ...
Uncovering the signal transduction pathway that regulates the proliferation of Dictyostelium cells
AprA (Autocrine Proliferation Repressor) is a secreted factor that represses proliferation in the slime mold Diclyostelium discoideum . Although the role AprA plays in the regulation of proliferation is known, the signaling ...
Characterization of the stimulation of SNARE-mediated membrane fusion by the SM protein Munc18a
The mammalian neuronal Sec1p/Munc18 protein Muncl8a binds tightly to the t-SNARE Syntaxin1a in isolation, and the binary Muncl8a/Syntaxin1a interaction is thought to prevent formation of the Syntaxin1a/SNAP25b t-SNARE ...