Now showing items 1-4 of 4
Monte Carlo simulation studies of DNA hybridization and DNA-directed nanoparticle assembly
A coarse-grained lattice model of DNA oligonucleotides is proposed to investigate how fundamental thermodynamic processes are encoded by the nucleobase sequence at the microscopic level, and to elucidate the general ...
Insights into peroxisome matrix protein import and IBA metabolism through analysis of IBA-response mutants
Peroxisomes are single membrane-bound organelles that function to compartmentalize certain metabolic reactions critical to plant and animal development. I have studied peroxisomal processes in the model plant Arabidopsis ...
Metabolic engineering of the flow of reducing equivalents for the production of biochemicals in Escherichia coli
In the present thesis, metabolic engineering principles have been applied to strategically design E. coli strains with improved characteristics for the production of biochemicals. The metabolic engineering discipline ...
Single-molecule FRET analysis of the dynamics of AMPA receptor
Single-molecule fluorescence resonance energy transfer (smFRET) spectroscopy has advanced to become a powerful tool in characterizing biomolecules to the molecular level. In this thesis, the smFRET technique was utilized ...