Now showing items 1-3 of 3
Nanoshells in vivo imaging using two-photon excitation microscopy
This thesis describes the development and optical characterization of near infrared (NIR) gold nanoshells for the use as luminescent contrast agents for applications in small animal blood vessel imaging. Two types of ...
Enhanced sampling method for free energy calculation and large scale conformational change
A method of directly computing the partition function (or the corresponding free energy) and accelerating configurational sampling is developed. In an expanded ensemble, the method can quickly sample a broad distribution ...
Knowledge-based prediction of chemical shift and recognition of protein native structure
We designed and implemented a suite of program which is able to accurately and automatically predict chemical shift of protein C-alpha nuclei on the simple basis of protein sequence and low-resolution C-alpha trace ...