Now showing items 1-6 of 6
The thermal rearrangement of 2,2'-bismethylenebicyclopropane
2,2$\sp\prime$-Bismethylenebicyclopropane rearranges to 6-methylenespiro (2.4) hept-4-ene and 3,6-bismethylenecyclohexene in solution at 195$\sp\circ$C. The formation of six dimers is also observed. 2,2$\sp\prime$-Bismet ...
Synthetic studies toward the total synthesis of (+)-anthramycin total syntheses of (+)-neothramycins A and B
Through the serendipitous discovery of a palladium catalyzed conversion of ethylthiol esters to their corresponding aldehydes, the pyrrolo (1,4) benzodiazepine systems found in (+)-anthramycin 1a* and (+)-neothramycins A ...
Investigation of multiple quantum coherence transfer in two-dimensional NMR spectroscopy
The limitations of zero quantum NMR pulse sequences reported in the literature are discussed. Several new pulse sequences which improve and extend the scope of the currently available pulse sequences are described. A ...
Synthetic applications of the aza-Achmatowicz rearrangement
A novel method for the enantioselective synthesis of nitrogen containing compounds has been achieved. The oxidative rearrangement of N-acyl 2-furylamines, termed the Aza-Achmatowicz rearrangement, generates a product with ...
Studies on the synthesis and properties of cyclopropenes
Tetra-n-butylammonium fluoride supported on glass helices was used to generate cyclopropenes in the gas phase from $\beta$-halocyclopropylsilanes using the vacuum gas-solid reaction (VGSR) technique. Bicyclo (4.1.0) ...
Total synthesis of mitomycins
The total synthesis of mitomycins via isomitomycin A is described. Key reactions are a Michael-type coupling reaction between chalcone (94)* and 5-ethylthio-2-trimethylsiloxyfuran, followed by an azido-olefin cyclization. ...