Now showing items 1-5 of 5
Video microscopy and digital image processing applied to tissue engineering: Intracellular ion and cell adhesion measurements
To provide a fundamental understanding of the structure/function relationship of cells and tissues, engineers have had to bridge the two worlds of engineering and of molecular and cell biology. Through this multidisciplinary ...
Macromolecular permeability of endothelial cells subjected to biochemical and mechanical stimuli
Endothelial cells line all of the vessels of the circulatory system, providing a non-thrombogenic conduit and form the principal barrier to the transport of substances between the blood and the surrounding tissue. The ...
Receptor mediated adhesion of sickle erythrocytes and damage to IL-1 beta stimulated endothelial cells under flow conditions in vitro
Enhanced, abnormal adherence of sickle erythrocytes to the endothelium lining blood vessels is hypothesized to contribute to vasoocclusion in sickle cell patients, but the specific molecular mechanisms by which these ...
Flow induced regulation of endothelial nitric oxide synthase (eNOS) gene expression: Role of shear sensitive promoter elements
Vascular endothelium responds to hemodynamic forces such as shear stress by altering the synthesis and genetic expression of several proteins. Shear stress sensitive promoter elements and transcription factors may be ...
Tumor cell adhesion stabilization: Regulation and relationship to organ-specific metastasis
Tumor cell arrest and the formation of stable adhesive interactions between tumor cells and endothelial cells or underlying matrix in the microvasculature are crucial steps in the metastatic process. A sensitive hydrodynamic ...