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Self-Assembling MultiDomain Peptides as Scaffolds for Tissue Engineering
Creating a new generation of biomaterials to support tissue engineering efforts is critical to the development of functional tissues. This thesis describes the initial phases of biomaterial development of seven new MultiDomain ...
Tailored Release of Bioactive Factors from Composite Multidomain Peptide Hydrogels
Multidomain peptides (MDP) self-assemble to form nanofibrous scaffolds well suited to tissue engineering and regeneration strategies. MDPs can present bioactive cues that promote vital biological responses. Orthogonal ...
Development of Multidomain Peptide Hydrogels for Tissue Engineering Applications
Over the past decade, multidomain peptides (MDP) have been designed, synthesized, and customized for tissue engineering applications. The goals of this work were twofold: 1) to develop novel MDP hydrogels with unique ...
Design, Structure and Applications of Collagen-Mimetic Peptides
The collagen triple helix is a unique protein fold found in all domains of life where is has diverse roles from imparting structure and strength to tissue, to initiating an immune response. While many factors affecting the ...