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Characterization and application of a periplasmic protein releasing system for extracellular recombinant protein production in Escherichia coli
Escherichia coli is commonly used as a host in the production of high value therapeutic proteins. However, one major drawback associated with E. coli being a host is the intracellular location of product proteins. As a ...
Sensitivity analysis of a mechanistic growth model of Escherichia coli
A detailed mechanistic model, with a large number of metabolites and parameters, describing growth of a single cell of the bacterium Escherichia coli is simulated and the resulting predictions are compared with available ...