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Metabolic engineering of acetate-production pathways for the production of isoamyl acetate and succinate in Escherichia coli
Products derived from the central aerobic metabolic pathway in Escherichia coli often compete with the acetate-producing pathways poxB and ackA-pta for glucose. The production of isoamyl acetate from acetyl-CoA by ATF2, ...
Application of metabolic and biochemical engineering techniques to enhance metabolic flux throughput and improve succinate production in Escherichia coli
Using biochemical engineering principles and metabolic engineering tools in tandem can considerably improve process productivity by manipulation of the throughput of certain pathways. Escherichia coli was chosen as the ...