Now showing items 1-5 of 5
Migration of anchorage-dependent mammalian cells
Cell migration affects many physiologic and pathologic processes in mammalian organisms. Thus, our ability to modulate these processes depends on understanding how cell migration is controlled by soluble factors, cell-substrate ...
2D timelapse and 3D fluorescence microscopy with applications to vascular tissue engineering
Part of the definition given to the new emerging science discipline of tissue engineering is the understanding of the structure-function relationships at the cellular level. In this context it is important for vascular ...
Development of poly(propylene fumarate-co-ethylene glycol): An injectable, biodegradable implant for cardiovascular applications
A novel block copolymer consisting of poly(propylene fumarate), PPF, and poly(ethylene glycol), PEG, was fabricated and evaluated for use as a cardiovascular stent to prevent reclosure of the vessel lumen following balloon ...
Molecular mechanisms of platelet thrombosis under arterial shear conditions
Pathologic arterial thrombosis is the leading cause of death in many countries. Current therapies provide only moderate protection from heart attack, stroke, and other clinical manifestations of thrombosis. To develop more ...
Molecular mechanisms of monocyte adhesion to endothelial cells under flow conditions
Monocyte adhesion to the endothelium is one of the earliest events leading to the pathogenesis of various inflammatory disorders like atherosclerosis. Since these interactions normally occur in flowing blood, it becomes ...