Now showing items 1-3 of 3
Effect of nonsteroidal anti-inflammatory drugs on the mechanical and electrical stability of phospholipid membranes
Non-steroidal anti-inflammatory drugs (NSAIDs) display powerful anti-inflammatory, analgesic and anti-pyretic activities. Serious side effects of NSAIDs, such as gastrointestinal (GI) bleeding and peptic ulcer disease, ...
Crystallographic refinement of thermal parameters using normal modes
We have developed a software package that models the anisotropic temperature factors of protein structures derived from crystallographic data using normal mode vectors. We hypothesize that the intrinsic flexibility of a ...
Poly(ethylenimine) as a gene delivery vehicle, and its potential for gene therapy
Poly(ethylenimine) (PEI) is a polycation with proven success as a gene delivery vehicle both in vitro and in vivo. The work described herein addresses several aspects of PEI-mediated gene delivery. First, a model system ...