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Additional insights into the structure and function of adenosine deaminase
Adenosine deaminase is a key enzyme in purine catabolism. The elucidation of the crystal structure and recent analysis of site-directed mutants have provided details on the structure and function of the enzyme. The studies ...
Investigations of neplanocin a reductase, an enzyme involved in aristeromycin biosynthesis
The nucleoside antibiotics aristeromycin and neplanocin A are two naturally occurring carbocyclic analogs of adenosine produced by Streptomyces citricolor. Partial purification of the crude cell-free extracts of S. citricolor ...
Identification and characterization of the xyloglucan endotransglycosylases of Arabidopsis thaliana
The plant cell wall is a fundamental determinant of cell shape, and therefore plant form. Although the molecular basis of plant morphology is unknown, it most likely involves enzymes capable of modifying different components ...
Apoglobin stability and ligand movements in mammalian myoglobins
The design of recombinant globins as oxygen storage and delivery pharmaceuticals must address two key protein engineering problems, one dealing with the improvement of apoprotein stability and the other with the structural ...