Now showing items 1-6 of 6
Mechanisms of frequency-entrainment in neuromodulated, synaptically driven pacing and bursting cells
The development of quantitative models that describe how neural inputs control the electrophysiological behavior of two cellular oscillators is presented. These cellular oscillators are a spontaneously beating mammalian ...
Quantifying information coding limits in sensory systems
Neurons code information about sensory stimuli temporally in the times of occurrence of action potentials as well as spatially in the joint discharge patterns of neurons within an ensemble. In this work, we present a ...
Adaptive regularization based on noise estimation and its application to the inverse problem in electrocardiography
The inverse problem was solved to reconstruct endocardial electrograms from cavitary electrograms measured with a noncontact multielectrode probe. Noise levels were estimated at each time instant by extrapolating noise ...
A model of the aortic baroreceptor in rat
The baroreceptor, a stretch-sensitive neuron, senses static and dynamic arterial blood pressure and responds by producing a frequency-modulated train of action potentials. The size and anatomy of baroreceptor nerve endings ...
Mechanisms of repolarization and conduction in a mathematical model of electrophysiological responses in the human atrium
We have developed a mathematical model of the human atrial myocyte, based on averaged voltage-clamp data recorded from isolated single myocytes. This formulation can reconstruct action potential data which are representative ...
Modeling and analyzing fractal point processes
The temporal pattern of the action potential discharges of auditory nerve fibers have been presumed to be random in nature and well described as a renewal process. Recently, we observed that the discharges were characterized ...