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Platelet interactions with subendothelial surfaces under physiological shear conditions: Response to type VI collagen and an endothelial cell wound model
The elucidation of the molecular mechanisms of platelet adhesion and aggregation in response to naturally occurring subendothelial surfaces under flow conditions is important medically in atherosclerosis and mural thrombosis. ...
Tumor cell adhesion: Dynamic adhesion of RAW117 lymphoma to organ-specific endothelial cells and the development of an invasion assay
The role of cell adhesion molecules was explored in a model of hematogenous metastasis. RAW117 lymphoma cells were perfused over hepatic sinusoidal endothelial (HSE) and murine microvascular lung endothelial (MLE) monolayers ...
Effects of dynamic mechanical stresses on mammalian cell metabolism
The effects of dynamic mechanical stresses on the arachidonic acid (AA) metabolism of human platelets and on the cell growth properties of murine tumor cells were studied. The cells were stressed by suspending them in ...