Now showing items 1-4 of 4
Effects of mechanical loading on osteoblast function using a three dimensional celijpolymer model
Mechanisms which trigger bone modeling/remodeling in response to changes in the mechanical environment are still unclear. In a three part study, effects of loading on osteoblast function were investigated using a three ...
Effect of novel antithrombotic agents on platelet aggregation under flow conditions
Epi-fluorescence video microscopy and digital image processing were used to evaluate the effects of three novel anti-platelet agents namely GT-12/I.2HBr (GT-12/I), A4.2HBr and IC, a series of compounds containing the ...
Dynamic mathematical modeling of mural thrombogenesis over type I collagen
We have developed a transient computational model of mural thrombogenesis, simulating whole blood flow in real time in a parallel plate flow chamber. Finite element computational methods were utilized to solve governing ...
Flow induced regulation of endothelial nitric oxide synthase (eNOS) gene expression: Role of shear sensitive promoter elements
Vascular endothelium responds to hemodynamic forces such as shear stress by altering the synthesis and genetic expression of several proteins. Shear stress sensitive promoter elements and transcription factors may be ...