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Growth and injury of freely suspended animal cells in an agitated and surface-aerated bioreactor
The mechanism of animal cell damage due to agitation and aeration in a stirred bioreactor and the effect of media components on cell damage were investigated. Hybridoma cells ATCC CRL-8018 were grown in controlled bioreactors ...
Permeability of endothelial monolayers under stationary and flow conditions
In vivo and ex vivo studies with whole vessels demonstrated that the endothelium comprises the major permeability barrier in the blood vessel wall. As a lining between the blood and the underlying tissue, the endothelium ...