Now showing items 31-35 of 35
Orthogonal approaches for studying glycosaminoglycan biopolymer
The evolution of glycosaminoglycans (GAGs) in eukaryotic species has been one of great biological mysteries. This thesis investigates the composition, rate of degradation and solution characteristics of aggrecan proteoglycan ...
Promotion and control of angiogenic activity in poly(ethylene glycol) diacrylate hydrogels for tissue engineering applications
Promotion and control of angiogenic activity have been achieved by covalently linking an angiogenic-signaling protein or peptide to poly(ethylene glycol) diacrylate hydrogels, thereby yielding a system which can be used ...
Characterization of chondrocytic differentiation and optimization of a self-assembling process for tissue engineering of articular cartilage
Articular cartilage degeneration, which occurs due to trauma or disease, results in the formation of tissue with inferior structural and mechanical properties. Tissue engineering has been proposed as a method to aid in the ...
Delivery of molecular-specific optical contrast agents for cancer biomarker detection in live cells and tissues
Molecular-specific optical contrast agents have shown promise as potential non-invasive probes for the detection of cancer and its precursors. The topical use of optical contrast agents in vivo has been hindered, however, ...
Mechanical stimulation towards tissue engineering of the knee meniscus
Tissue engineering has been proposed to alleviate injury to the knee meniscus, which leads to loss of function and damage to the surrounding articular cartilage. Relatively few studies have been performed to tissue engineer ...