Now showing items 21-30 of 814
Investigations in the lactose repressor core domain: Characterization of the tryptophans and the inducer binding site
The lactose repressor protein, the prototypic genetic control element, contains two tryptophan residues at positions 201 and 220. We have utilized site-specific mutagenesis techniques to generate mutant lac repressors with ...
High temperature studies of diamond and CVD diamond thin films
The extreme hardness, thermal conductivity and molar density of diamond make it an important technological and industrial material. For some applications, thin films of diamond are desired, but the low quality of such films ...
New synthetic reactions: Applications to discorhabdins and carbacephems
A novel approach for the synthesis of antitumor agents Discorhabdins (1) is described. The synthetic route features a new Paterno-Buchi photo reaction for the spirocyclic ring preparation and cascade Michael reactions for ...