Now showing items 11-20 of 139
Metabolic engineering and flux analysis of Escherichia coli
The advances in molecular biology, genome sequencing and mathematical tools have led to growing interest in metabolic engineering, the goal of which is to redirect metabolic fluxes for industrial and medical purposes. ...
Studies on the effects of temperature, pH, and anaerobiosis on gene expression in E. coli K-12
This research investigated the effects of temperature, pH, and anaerobiosis on gene expression in Escherichia coli. In the first series of experiments, the effects of FirA, a histone-like protein, and two temperature ...
Interactions of heme with apomyoglobin and lipid bilayers
CO-heme interactions with sperm whale apomyoglobin (apoMb) and model membrane systems were examined by spectroscopic and kinetic techniques. The binding of heme to apoMb appears to be a simple bimolecular process at ...
Structural determinants of functional behavior in distal pocket mutants of myoglobin
The physiological role of myoglobin depends on the modulation of heme activity by the protein. The hypothesis that functional properties are governed by conserved residues in the distal pocket has been tested by site-directed ...
Syntheses and coenzymatic activities of analogs of vitamin C
Abstract Not Available.
Syntheses, bioactivities and conformations of peptidomimetics containing 2,3-methanoamino acids
Asymmetric syntheses of E- and Z-2,3-methanomethionine (ie E- and Z-cyclo-Met), protected Z-2,3-methanoarginine, and Z-2,3-methanoaspartic acid derivatives have been developed. These functionalized 2,3-methanoamino acids ...
Characterization and modeling of the pH-regulated expression vector, pSM-10
A new type of plasmid vector has been developed for Escherichia coli. Foreign gene expression can be altered by external pH changes. pSM-10 is the first generation of these plasmid constructs that utilizes the cadA operon ...