Now showing items 11-20 of 304
Receptor-specific binding of von Willebrand factor to platelets in response to shear stress
Physical and biochemical forces convert platelets in human blood in vivo from the quiescent state as freely moving, discoid, singlets to aggregates adhering to subendothelial surfaces and secreting a wide variety of bioactive ...
Studies on Escherichia coli tryptophan repressor-operator interactions
Trp repressor regulates the expression of TrpEDCBA, aroH, and TrpR operons. Recently, X-ray crystallographic analysis of a Trp repressor-operator complex has suggested a stoichiometry of one repressor dimer to one operator ...
A simple and effective model to study insulin resistance in obesity and diabetes and the processes and mechanisms of in vitro aging using lymphocyte culture
Cell culture provides a simple and effective system to study metabolic and cellular processes required for cellular growth in vitro. In this study, we demonstrate that lymphocyte culture can be used as a model system to ...
Analysis of HeLa cell premessenger RNA splicing complexes containing the snRNP U1 by native gel electrophoresis
The typical eukaryotic RNA polymerase II primary transcript is divided into regions that encode information expressed at the protein level (exons) and those which do not (introns). The latter must be removed from the ...
Ligand and genetic studies of the sulfate-binding protein and characterization of the calcium-binding site in the galactose-binding protein
The effect of pH on the binding affinities of the conjugate bases of four different tetrahedral oxyacids to the periplasmic sulfate-binding protein from Salmonella typhimurium has been determined. In light of the highly ...
The vascular system of the rabbit ovary and its relationship to ovulation
Abstract Not Available.
Studies on the lipid metabolism of cestodes
The problem of the energy relationship is fundamental in any investigation of animal physiology. Endoparasitic helminths present a rather unique ecological situation since the energy sources and substrates for the parasite ...
The production of mutations in Drosophila melanogaster by irradiation with alpha-rays
The artificial transmutation of the gene is an old problem. Investigators tried to produce mutations artificially, but failed until 1927 when Muller announced that gene mutations could be produced by means of X-rays. This ...