Now showing items 11-15 of 15
Investigation of the role of Wee2 in the zebrafish midblastula transition
Zebrafish embryonic development begins with a series of rapid and synchronous cell divisions that quickly partition the zygote into a set of small blastomeres. The minimal cell division cycle during this period consists ...
AprA: An autocrine, secreted factor that represses cell proliferation in Dictyostelium discoideum
Dictyostelium cells secrete factors during growth and starvation. AprA (autocrine proliferation repressor), a 60 kDa protein secreted as part of a 150 kDa protein complex, functions as a cell proliferation repressor. In ...
Monitoring iron-sulfur cluster content of human glutaredoxin 2 using fluorescence proteins
Current methods for directly determining whether an iron-sulfur cluster has been synthesized on a protein in vivo typically require that the protein of interest is purified prior to analysis for bound metallocluster. To ...
Molecular genetic analyses of plant peroxisome functions
Arabidopsis peroxisomes carry out diverse functions, including fatty acid β-oxidation and conversion of indole-3-butyric acid (IBA) to indole-3-acetic acid (IAA). Peroxins are proteins necessary for peroxisome biogenesis; ...
Exploration of DNA binding selectivity, transcriptional regulation, and evolutionary relationships of the Hox protein Ultrabithorax
Hox transcription factors direct differentiation in all tissue layers and many organ systems and therefore have highly specific tissue-dependent functions. The DNA-binding homeodomain of Hox proteins can bind a wide array ...