Now showing items 1-5 of 5
Receptor-specific binding of von Willebrand factor to platelets in response to shear stress
Physical and biochemical forces convert platelets in human blood in vivo from the quiescent state as freely moving, discoid, singlets to aggregates adhering to subendothelial surfaces and secreting a wide variety of bioactive ...
Flow induced regulation of endothelial nitric oxide synthase (eNOS) gene expression: Role of shear sensitive promoter elements
Vascular endothelium responds to hemodynamic forces such as shear stress by altering the synthesis and genetic expression of several proteins. Shear stress sensitive promoter elements and transcription factors may be ...
Nonlinear model of external respiration
A mathematical model of the external respiratory system is presented which integrates component models of airway mechanics and gas exchange at the pulmonary capillaries. The respiratory system is lumped into: (1) a conducting ...
Video microscopy and digital image processing applied to tissue engineering: Intracellular ion and cell adhesion measurements
To provide a fundamental understanding of the structure/function relationship of cells and tissues, engineers have had to bridge the two worlds of engineering and of molecular and cell biology. Through this multidisciplinary ...
Macromolecular permeability of endothelial cells subjected to biochemical and mechanical stimuli
Endothelial cells line all of the vessels of the circulatory system, providing a non-thrombogenic conduit and form the principal barrier to the transport of substances between the blood and the surrounding tissue. The ...