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The kinetics of human platelet aggregation and disaggregation in controlled shear fields
The objectives of this research are to contribute to a better understanding of human platelet involvement in vascular disease. To accomplish this, both the laser light scattering technique and the population balance equation ...
A study on the resistances to oxygen transport in the microcirculation
A study on the resistances to oxygen transport in the microcirculation has been conducted. In Part I of this work, the oxygen permeability of cultured bovine aortic and human umbilical vein endothelial cell monolayers was ...
Effect of laminar shear stress on gene regulation, protein synthesis, and protein secretion by cultured human endothelial cells
To test the hypothesis that wall shear stress generated by blood flow may regulate endothelial cell expression of blood clot dissolving proteins or vasoactive proteins, an in vitro perfusion system was used to expose human ...
Dynamic mathematical modeling of mural thrombogenesis over type I collagen
We have developed a transient computational model of mural thrombogenesis, simulating whole blood flow in real time in a parallel plate flow chamber. Finite element computational methods were utilized to solve governing ...