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The Role of Base Modifications on Tyrosyl-tRNA Structure, Stability, and Function in Bacillus subtilis and Bacillus anthracis
tRNA molecules contain more than 80 chemically unique nucleotide base modifications that contribute to the chemical and physical diversity of RNAs as well as add to the overall fitness of the cell. For instance, base ...
Anticipation of Nitric Oxide Stress in the Human Commensal Fungus Candida albicans
Candida albicans is the most common human commensal fungus, able to colonize host niches such as skin, mouth and gastrointestinal tract. Colonization of diverse microenvironments requires the ability to evade or overcome ...
Structure of the hepatitis E virus-like particle suggests me chanisms for virus assembly and receptor binding
This thesis reports the atomic structure of the Hepatitis E virus (HEV) in the form of a virus-like particle (VLP). HEV is a small, non-enveloped RNA virus in the family Hepeviridae and is the principal cause of endemic ...