Now showing items 1-6 of 6
Studies of platelet glycoprotein Ib-IX-V adhesion tovon Willebrand factor using optical tweezers
The first stage in hemostasis and thrombosis is the binding of the platelet membrane receptor, glycoprotein (GP) Ib-IX, to its ligand, von Willebrand factor (VWF), in the subendothelium. Using an optical tweezers system, ...
Selective vascular injury during cutaneous laser therapy
Pulsed laser irradiation in conjunction with cryogen spray cooling (CSC) can induce selective vascular injury to remove cutaneous hypervascular malformations such as port wine stains (PWS), hemangiomas, and facial veins. ...
Optical characterization and in vivo assessment of charge-assembled capsules containing indocyanine green for laser-mediated diagnosis and therapy
We have developed a carrier system to encapsulate Indocyanine Green (ICG) to overcome its limitations for laser-mediated medical applications. Charge-assembled capsules with controllable size and adjustable coatings ...
Optimization of cryogen spray cooling: Increasing epidermal protection during cutaneous laser procedures
Cryogen spray cooling (CSC) is an effective method to minimize epidermal damage during laser treatment of various cutaneous anomalies such as port wine stains (PWS). We examined the mechanism of heat removal by CSC from ...
Analysis of mechanical characteristics of plasma membranes using optical tweezers
In this thesis work an optical tweezers system was designed and used to characterize viscoelastic response of plasma membranes (PMs) to an applied stress under different environmental conditions. In order to perform accurate ...
Quantification of staphylococcal adhesion using optical tweezers
Biofilm formation, a common cause of medical device failure and tissue infection, often follows bacterial adhesion to proteins present in the tissue or adsorbed on the implant surface. Certain species of gram-positive ...