Now showing items 1-2 of 2
Functional and structural studies of the Influenza A virus polymerase subunit PB1 and its complex with the PA subunit
The influenza virus RNA polymerase is a heterotrimeric complex of PA, PB1, and PB2. PB1 functions in RNA elongation, 5' and 3' viral RNA binding, and has an endonuclease activity. For detailed biochemical and structural ...
The study of an autocrine signal transduction pathway that represses cell proliferation in Dictyostelium discoideum
Many secreted factors are believed to inhibit cell proliferation in certain tissues such as tumors; however, the identity and action of most of these factors remains unknown. The recent identification of two autocrine ...