Now showing items 1-5 of 5
Receptor-specific binding of von Willebrand factor to platelets in response to shear stress
Physical and biochemical forces convert platelets in human blood in vivo from the quiescent state as freely moving, discoid, singlets to aggregates adhering to subendothelial surfaces and secreting a wide variety of bioactive ...
Bone formation by three-dimensional osteoblast culture in biodegradable poly(alpha-hydroxy ester) scaffolds
The feasibility of culturing osteoblasts on biodegradable poly($\alpha$-hydroxy esters) to form new bone was investigated through a series of five studies. The first study demonstrated that rat calvarial osteoblasts attached, ...
Polymeric delivery of inhibitors of smooth muscle cell proliferation
Restenosis, currently estimated to occur in 30-50% of dilated lesions, continues to be a major limitation to the success of current interventional cardiovascular procedures. Presently, no established therapy prevents or ...
Hydrodynamic and molecular dependence of neutrophil-neutrophil adhesion
Homotypic adhesion of neutrophils stimulated with chemoattractant is analogous to capture on vascular endothelium in that both processes depend on L-selectin and $\beta\sb2$-integrin adhesion receptors. Under hydrodynamic ...
Video microscopy and digital image processing applied to tissue engineering: Intracellular ion and cell adhesion measurements
To provide a fundamental understanding of the structure/function relationship of cells and tissues, engineers have had to bridge the two worlds of engineering and of molecular and cell biology. Through this multidisciplinary ...