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Leveraging Biomaterials for the Treatment of Large Infected Tissue Defects
While the body has an incredible ability to heal, host and external factors may overwhelm its innate regenerative capacity. In these instances, a tissue defect may occur. Tissue defects (regions of either necrotic tissue ...
Biodegradable Hydrogel Composites for Growth Factor and Stem Cell Delivery in Osteochondral Tissue Engineering
Cartilage has a limited endogenous ability for self-repair and current clinical treatments for damaged or diseased cartilage tissue are insufficient. Additionally, there is a biological and mechanical interplay between ...
Adeno-Associated Virus-Based Gene Delivery Approaches for Tissue Engineering
Tissue engineering constitutes non-trivial processes that can be promoted through combinations of cells, materials and bioactive factors. The formation of tissues and organs demands spatiotemporal precision that cannot, ...