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Role oflac repressor hinge region and operator DNA sequence in complex formation
A study of the lac repressor hinge region was undertaken to decipher its role in the function of DNA binding and communication between binding sites within the protein. Specific mutations were designed, and the proteins ...
Structural consequences of base modifications and metal iron interactions on the anticodon stem-loop from tRNA(Phe) (Escherichia coli)
The structural effects of naturally modified bases of RNA are mostly uncharacterized. The structural effects of two base modifications and of cations in the anticodon stem loop of tRNAPhe (Escherichia coli) were studied ...
Cloning of terpene synthases from plants
As part of a program to clone Artemisia annua sesquiterpene biosynthetic genes, a cDNA encoding epi-cedrol synthase was isolated from an A. annua leaf cDNA library by a homology-based strategy. The cDNA was functionally ...