Now showing items 1-5 of 5
A gene therapy approach for tissue engineering applications
In this work, gene therapy was combined with cell therapy to tackle three tissue engineering applications. The goal of the first project was to promote endothelialization of tissue engineering vascular grafts (TEVGs). We ...
Collagenous tissue engineered constructs to investigate the role of decorin on collagen fibrillogenesis and tissue mechanics
Decorin, a small leucine rich proteoglycan, has been reported to control collagen fibrillogenesis, thereby influencing the tensile properties of collagenous tissues. In this research work, decorin deficient cells (Dcn -/- ...
Targeting A549 and MCF7 with small bivalent molecules coated on liposomes
Bilamellar invaginated vesicles (BIVs) are liposomal/nanopartical delivery vehicles that have the ability to penetrate tight barriers throughout the target organ including the interstitial pressure gradient in large solid ...
Mechanical characterization, gene expression, and biosynthesis of the porcine TMJ disc for the purposes of tissue engineering
The temporomandibular joint (TMJ) may be permanently damaged by disease or trauma; thus, TMJ cartilage is a prime target for tissue engineers. The damaged TMJ disc may become obstructive to normal jaw function, leading to ...
Mechanical stimulation towards tissue engineering of the knee meniscus
Tissue engineering has been proposed to alleviate injury to the knee meniscus, which leads to loss of function and damage to the surrounding articular cartilage. Relatively few studies have been performed to tissue engineer ...