Now showing items 1-4 of 4
Collagenous tissue engineered constructs to investigate the role of decorin on collagen fibrillogenesis and tissue mechanics
Decorin, a small leucine rich proteoglycan, has been reported to control collagen fibrillogenesis, thereby influencing the tensile properties of collagenous tissues. In this research work, decorin deficient cells (Dcn -/- ...
Endothelial cell and mural progenitor cell co-culture to promote angiogenesis in tissue engineered constructs
The need for tissue engineered organs is great since only 15% of those on the transplant waiting list received organs in 2006. The ability to vascularize a tissue engineered construct is one of the major hurdles for tissue ...
Characterization of chondrocytic differentiation and optimization of a self-assembling process for tissue engineering of articular cartilage
Articular cartilage degeneration, which occurs due to trauma or disease, results in the formation of tissue with inferior structural and mechanical properties. Tissue engineering has been proposed as a method to aid in the ...
Delivery of molecular-specific optical contrast agents for cancer biomarker detection in live cells and tissues
Molecular-specific optical contrast agents have shown promise as potential non-invasive probes for the detection of cancer and its precursors. The topical use of optical contrast agents in vivo has been hindered, however, ...