Now showing items 1-6 of 6
A gene therapy approach for tissue engineering applications
In this work, gene therapy was combined with cell therapy to tackle three tissue engineering applications. The goal of the first project was to promote endothelialization of tissue engineering vascular grafts (TEVGs). We ...
Self assembly of fibrochondrocytes and human embryonic stem cells for tissue engineering of fibrocartilage
Injuries to the fibrocartilage of the knee, the medial and lateral menisci, present a particular challenge: the tissue is incapable of self-repair and the long-term outcomes of meniscectomy are osteoarthritis and disability. ...
Photothermal therapies using near infrared absorbing nanoparticles
This thesis describes the development of new infrared (NIR) absorbing nanoparticles for use in biomedical therapeutic applications. Gold nanoshells with a dielectric core of silica developed at Rice University have shown ...
Chondrocyte biomechanics and chondrogenesis
This thesis contributes to two aspects of cartilage research: understanding the biomechanical characteristics of single chondrocytes, and tissue engineering musculoskeletal cartilages with human embryonic stem cells (hESCs). ...
Development of injec table nanocomposite scaffolds of single -walled carbon nanotubes and biodegradable polymers for bone tissue engineering
Nanocomposites based on single-walled carbon nanotubes (SWNTs) and poly(propylene fumarate) (PPF) were developed and characterized as injectable scaffold materials for bone tissue engineering. Similar to other synthetic ...
Targeting A549 and MCF7 with small bivalent molecules coated on liposomes
Bilamellar invaginated vesicles (BIVs) are liposomal/nanopartical delivery vehicles that have the ability to penetrate tight barriers throughout the target organ including the interstitial pressure gradient in large solid ...