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Computational and Theoretical Analysis of Influenza Virus Evolution and Immune System Dynamics
Influenza causes annual global epidemics and severe morbidity and mortality. The influenza virus evolves to escape from immune system antibodies that bind to it. The immune system produces influenza virus specific antibodies ...
Computational Biology: Insights into Hemagglutinin and Polycomb Repressive Complex 2 Function
Influenza B virus hemagglutinin (HA) is a major surface glycoprotein with frequent amino-acid substitutions. However, the roles of antibody selection in the amino-acid substitutions of HA were still poorly understood. An ...