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HEME TRANSPORT AND INCORPORATION INTO GLOBIN
The mechanism of heme uptake and release by cell membranes and proteins was investigated using a model system of carbon monoxide heme, human globin, and phosphatidyl choline single bilayer vesicles. The combination of heme ...
ENZYMATIC SYNTHESIS OF THE 2-DEOXYSTREPTAMINE MOIETY OF GENTAMICIN AND RELATED ANTIBIOTICS. CHARACTERIZATION OF A GLUTAMINE: AMINOCYCLITOL AMINOTRANSFERASE
A soluble, stable, L-glutamine:aminocyclitol aminotransferase has been purified 100-fold from mature mycelia of the gentamicin producer Micromonospora purpurea ATCC 15835. An absorbance maximum at 415 nm indicated the ...
Classes of polyadenylation sites revealed by native gel electrophoresis of in vitro assembled complexes and sensitivity to U RNA cleavage
The sequences that comprise a polyadenylation signal are varied. With the exception of the conserved hexanucleotide AAUAAA, other required sequence elements vary from site to site. This variability in sequence content may ...
Interaction of a helical peptide with membrane: Study of alamethicin
Alamethicin is a transmembrane ion channel at low concentration, and a lytic agent of cell membrane at high concentration. It is a small size polypeptide (20 amino residues), and contains a large section of amphiphilic ...
Kinetic barriers to ligand binding in myoglobin
Picosecond, nanosecond, and bimolecular reactions of ligands with myoglobins containing distal pocket mutations at positions 29, 45, 64, and 68 were examined at 20$\sp\circ$C, in 0.1 M potassium phosphate pH 7.0. The ...