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Development of an injectable, in situ crosslinkable, degradable polymeric carrier for osteogenic cell populations
An injectable, in situ crosslinkable, degradable polymeric carrier for osteogenic cell populations was developed. Specifically, a system for encapsulating marrow stromal osteoblasts in gelatin microspheres has been implemented ...
Pharmacologically active materials for localized nitric oxide therapy
Nitric oxide (NO) functions as a ubiquitous biological messenger and effector molecule. In humans, NO performs unique actions throughout the body; for example, NO may aid in the prevention of blood vessel re-occlusion, or ...
von Willebrand factor interaction with subendothelial collagens and platelet surface receptor GPIBalpha under shear conditions
The molecular mechanisms of binding interaction among von Willebrand factor, subendothelium and platelets under physiological shear conditions are important medically in hemostasis and thrombosis. By binding both subendothelial ...