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The effect of laminar fluid flow on thrombomodulin activity and gene regulation in human endothelial cells
(1993)
Endothelial cell biology has become a major area of research during the last decade. An increasing body of evidence suggests that the local mechanical forces arising from blood flow play a key role in the normal physiology ...
Cone-plate viscometric studies of neutrophil adhesion to the endothelial ligands E-selectin and ICAM-1
(2000)
Neutrophil adhesion to endothelium is prerequisite for extravasation and localization at inflammatory sites. In the vasculature this process occurs under conditions of hydrodynamic shear requiring that bonds formed between ...
Effects of mechanical loading on osteoblast function using a three dimensional celijpolymer model
(1998)
Mechanisms which trigger bone modeling/remodeling in response to changes in the mechanical environment are still unclear. In a three part study, effects of loading on osteoblast function were investigated using a three ...
Effects of viscous dissipation on hydrodynamic stability of viscoelastic fluids
(1972)
Two constitutive equations for viscoelastic fluids are examined in linearized hydrodynamic stability analysis for the effects of viscous dissipation, in plane Couette flow heated from below. All physical properties are ...
2D timelapse and 3D fluorescence microscopy with applications to vascular tissue engineering
(1998)
Part of the definition given to the new emerging science discipline of tissue engineering is the understanding of the structure-function relationships at the cellular level. In this context it is important for vascular ...
Fibronectin and von Willebrand factor mediated sickle erythrocyte adhesion to human endothelial cells under venous flow conditions
(1988)
Sickle erythrocytes have previously been demonstrated to be abnormally adhesive to human endothelial cells in both static incubation assays and under venous flow conditions. The extent to which human fibronectin and human ...
Effect of shear stress on leukocyte adhesion to vascular endothelium
(1988)
The effect of flow on the adhesion of neutrophils (PMNL) to vascular endothelium was investigated using a parallel plate flow chamber. Human umbilical vein endothelial cells (HUVEC) were cultured on a glass slide which was ...
Effect of shear stress on surface membrane potassium ion permeability of calf pulmonary artery endothelial cells (Potassium ion)
(1989)
This study aims to determine the effect of shear stress on membrane potassium (K$\sp+$) permeability in vascular endothelial cells. Cultured monolayers of calf pulmonary artery endothelial cells, preloaded with $\rm ...
Effect of novel antithrombotic agents on platelet aggregation under flow conditions
(1992)
Epi-fluorescence video microscopy and digital image processing were used to evaluate the effects of three novel anti-platelet agents namely GT-12/I.2HBr (GT-12/I), A4.2HBr and IC, a series of compounds containing the ...
Experimental and mathematical analyses of mural thrombogenesis under flow
(1989)
An epifluorescence video microscopy system, coupled with digital image processing techniques, and a computerized microphotometric measurement system were used to analyze the effects of two antithrombotic agents on surface ...