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Using forward genetics to elucidate peroxisome biogenesis and peroxisome-associated protein degradation in Arabidopsis thaliana
Peroxisomes are organelles that sequester certain metabolic pathways; many of these pathways generate H2O2, which can damage proteins. Little is known about how damaged or obsolete peroxisomal proteins are degraded. ...
Mutants defective in the peroxisome-tethered ATPase complex implicated peroxins in oil body utilization during Arabidopsis seedling development
Catabolism of fatty acids stored in oil bodies is essential for Arabidopsis seed germination and seedling development. In plants, this β-oxidation occurs exclusively in peroxisomes, conserved organelles that are delimited ...
Using forward genetics to identify novel Arabidopsis thaliana peroxisomal mutants
Peroxisomes are single-membrane-bound organelles responsible for key metabolic reactions needed for the development of many eukaryotes. Peroxisomes lack DNA and must import nuclear-encoded proteins from the cytosol. Genetic ...